目 录
第一章 概述
第一节 注射美容及其材料 ............................................................................................................................002
一、注射美容的定义与范畴 ......................................................................................................................002
二、注射美容材料 .....................................................................................................................................002
第二节 注射美容的发展与演变 ....................................................................................................................005
一、肉毒毒素的发展与演变 ......................................................................................................................005
二、填充材料的发展与演变 ......................................................................................................................006
第三节 临床常用注射美容技术 ....................................................................................................................012
一、自体脂肪移植 .....................................................................................................................................012
二、肉毒毒素注射 .....................................................................................................................................013
三、透明质酸注射 .....................................................................................................................................014
四、胶原蛋白注射 .....................................................................................................................................016
五、软骨微粒注射 .....................................................................................................................................019
六、脱细胞真皮基质微粒注射 ..................................................................................................................020
七、病理性瘢痕注射治疗 ..........................................................................................................................024
第四节 注射美容常见并发症 ........................................................................................................................028
一、人工填充材料注射并发症 ..................................................................................................................028
二、肉毒毒素注射并发症 ..........................................................................................................................032
三、脂肪注射术的并发症 ..........................................................................................................................035
第五节 注射美容技术的风险管控................................................................................................................049
一、常用注射填充材料及其风险管控 ......................................................................................................049
二、A型肉毒毒素及其风险管控 ...............................................................................................................052
第二章 助推器的研发与转化
第一节 助推器的研发....................................................................................................................................058
一、第一代恒压恒量微创颗粒脂肪注射移植装置 ..................................................................................058
二、第二代恒压恒量微创颗粒脂肪注射移植装置 ..................................................................................059
三、第三代恒压恒量微创颗粒脂肪注射移植装置 ..................................................................................061
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第二节 助推器实验研究 ...............................................................................................................................063
一、助推器在大鼠体内移植脂肪时的压力变化 ......................................................................................063
二、助推器在人面部自体脂肪移植中的压力变化 ..................................................................................064
三、助推器对自体脂肪移植成活率的影响 ..............................................................................................065
第三节 助推器临床转化 ...............................................................................................................................066
一、助推器用于脂肪移植 ..........................................................................................................................066
二、助推器用于瘢痕注射 ..........................................................................................................................068
三、其他 .....................................................................................................................................................069
第三章 面部美学分区
第一节 面部解剖特征与脂肪室 ....................................................................................................................073
一、皮肤 .....................................................................................................................................................073
二、脂肪室 .................................................................................................................................................076
三、浅表肌腱膜系统 .................................................................................................................................078
四、面部肌肉、间隙与支持韧带 ..............................................................................................................079
五、骨膜与深筋膜 .....................................................................................................................................082
六、颅面骨解剖 .........................................................................................................................................082
七、面部血管、淋巴及神经 ......................................................................................................................083
第二节 基于面部脂肪室的面部美学分区 ...................................................................................................085
一、面部脂肪室的再认识 ..........................................................................................................................085
二、面部美学分区 .....................................................................................................................................086
第四章 自体脂肪组织注射
第一节 脂肪移植助推器及其应用 .............................................................................................................093
一、脂肪移植助推器 .................................................................................................................................093
二、脂肪移植助推器的应用 ......................................................................................................................094
第二节 面部各部位脂肪注射 ........................................................................................................................101
一、额部注射 .............................................................................................................................................101
二、眉部注射 .............................................................................................................................................102
三、鼻部注射 .............................................................................................................................................104
四、唇部脂肪移植 .....................................................................................................................................106
五、颏部脂肪移植 .....................................................................................................................................107
六、鼻唇沟部脂肪移植 ..............................................................................................................................108
七、眶周脂肪移植 .....................................................................................................................................110
八、颊部注射 .............................................................................................................................................113
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九、颞部脂肪移植 .....................................................................................................................................115
十、耳部美学分区及脂肪移植 ..................................................................................................................117
第三节 脂肪注射隆乳....................................................................................................................................119
一、手术方法 .............................................................................................................................................119
二、典型病例 .............................................................................................................................................120
第四节 脂肪注射隆臀....................................................................................................................................123
一、臀部美学与解剖特点 ..........................................................................................................................123
二、臀部脂肪注射移植技术要点 ..............................................................................................................125
第五节 女性会阴部自体脂肪注射................................................................................................................126
一、概述 .....................................................................................................................................................126
二、女性会阴部自体脂肪注射 ..................................................................................................................128
第五章 肉毒毒素注射
第一节 肉毒毒素的基础知识 ........................................................................................................................137
一、肉毒毒素的发现和历史 ......................................................................................................................137
二、肉毒毒素的蛋白结构 ..........................................................................................................................138
三、肉毒毒素的药理及毒理机制 ..............................................................................................................138
四、肉毒毒素的制品 .................................................................................................................................141
第二节 肉毒毒素在整形美容的应用 ...........................................................................................................144
一、肉毒毒素对组织的作用 ......................................................................................................................144
二、肉毒毒素在整形美容方面的应用 ......................................................................................................144
第三节 肉毒毒素注射相关的肌肉解剖 .......................................................................................................146
一、面部肌肉的生理和解剖特性 ..............................................................................................................146
二、面部表情肌解剖 .................................................................................................................................147
三、面部协同肌和拮抗肌 ..........................................................................................................................152
第四节 肉毒毒素的临床应用及注意事项 ...................................................................................................154
一、肉毒毒素的保存和配制 ......................................................................................................................154
二、肉毒毒素注射的操作步骤 ..................................................................................................................155
三、临床应用的注意事项及禁忌证 ..........................................................................................................159
第五节 肉毒毒素的常用注射部位................................................................................................................162
一、额纹 .....................................................................................................................................................162
二、鱼尾纹 .................................................................................................................................................164
三、眉间纹 .................................................................................................................................................167
四、鼻背纹 .................................................................................................................................................169
五、口周纹 .................................................................................................................................................170
六、颏部凹坑 .............................................................................................................................................170
七、颈纹 .....................................................................................................................................................172
八、面部提升 .............................................................................................................................................173
九、露龈笑 .................................................................................................................................................178
十、咬肌肥大 .............................................................................................................................................180
十一、腓肠肌肥大（小腿粗大） ................................................................................................................182
十二、眼轮匝肌肥大 .................................................................................................................................184
十三、面部肌肉痉挛症 ..............................................................................................................................185
十四、斜方肌注射（瘦肩） ........................................................................................................................186
十五、腋臭症 .............................................................................................................................................186
十六、肉毒毒素的微滴注射（MicroBotox） ..............................................................................................188
十七、其他 .................................................................................................................................................189
十八、面部注射点及危险区域 ..................................................................................................................190
第六节 肉毒毒素注射的不良反应及处理 ...................................................................................................192
一、肉毒毒素注射的不良反应及并发症 ..................................................................................................192
二、肉毒毒素注射不良反应的对策 ..........................................................................................................193
三、肉毒毒素中毒及处理 ..........................................................................................................................194
第六章 透明质酸注射
第一节 透明质酸简介及性状特点................................................................................................................199
第二节 常见部位透明质酸注射方法 ...........................................................................................................201
一、额部 .....................................................................................................................................................201
二、颞部 .....................................................................................................................................................202
三、上睑凹陷 .............................................................................................................................................203
四、泪沟部及面中部（苹果肌） ................................................................................................................203
五、鼻部 .....................................................................................................................................................204
六、鼻唇沟 .................................................................................................................................................205
七、颊部 .....................................................................................................................................................206
八、唇部 .....................................................................................................................................................207
九、颏部 .....................................................................................................................................................207
十、颈部 .....................................................................................................................................................208
第三节 透明质酸的特殊注射方法................................................................................................................211
一、MD CodesTM注射法 ..............................................................................................................................211
二、水光注射 .............................................................................................................................................215
第四节 透明质酸注射的并发症及处理方法 ...............................................................................................217
第七章 胶原蛋白注射
第一节 可注射胶原蛋白概述 ........................................................................................................................221
一、可注射胶原蛋白特性 ..........................................................................................................................221
二、可注射胶原蛋白适应证与禁忌证 ......................................................................................................222
第二节 可注射胶原蛋白在眶周年轻化的临床应用 ..................................................................................224
一、术前评估及分型 .................................................................................................................................224
第三节 可注射胶原蛋白在面部紧致提升的临床应用 ..............................................................................228
一、术前评估及理念 .................................................................................................................................228
二、注射部位及注射点位技巧 ..................................................................................................................229
第四节 可注射胶原蛋白在美塑疗法的应用 ...............................................................................................230
一、胶原蛋白在美塑疗法的特性 ..............................................................................................................230
二、皮肤老化原因及其区别 ......................................................................................................................230
第五节 可注射胶原蛋白在轮廓修饰与美化的应用 ..................................................................................233
一、鼻部的注射技巧及注意事项 ..............................................................................................................233
二、额部的注射技巧及注意事项 ..............................................................................................................234
第六节 案例展示 ............................................................................................................................................235
第八章 软骨微粒注射
第一节 软骨微粒注射技术在鼻整形的应用 ...............................................................................................240
一、软骨微粒鼻整形应用的历史及进展 ..................................................................................................240
二、软骨微粒注射技术的创新性 ..............................................................................................................241
三、软骨微粒在鼻基底填充的应用 ..........................................................................................................244
第二节 细条状软骨注射技术在鼻整形的应用...........................................................................................246
一、从颗粒肋软骨到细条状肋软骨注射技术的转变 ..............................................................................246
二、细条状肋软骨注射技术的创新性 ......................................................................................................246
第九章 自体软组织匀浆注射
第一节 自体软组织匀浆器的研发................................................................................................................252
一、医用自体软组织匀浆器的技术参数 ..................................................................................................252
二、医用自体软组织匀浆器工作原理 ......................................................................................................253
三、医用自体软组织匀浆器的特点 ..........................................................................................................254
第二节 脱细胞真皮基质（ADM）匀浆的制备与应用 ............................................................................256
一、ADM匀浆的研究现状 .........................................................................................................................256
二、人ADM匀浆的制备与应用 .................................................................................................................260
第三节 人真皮匀浆的制备与应用................................................................................................................267
一、人真皮匀浆的制备 ..............................................................................................................................267
二、人真皮匀浆的应用 ..............................................................................................................................269
第四节 人脱细胞脂肪组织基质匀浆的制备与应用 ..................................................................................273
一、人脱细胞脂肪组织基质匀浆的制备 ..................................................................................................273
二、人脱细胞脂肪组织基质匀浆的应用 ..................................................................................................276
第五节 人脂肪组织匀浆的制备与应用 .......................................................................................................281
一、人脂肪组织匀浆的制备 ......................................................................................................................281
二、人脂肪组织匀浆的应用 ......................................................................................................................282
第十章 病理性瘢痕的注射治疗
第一节 生理性瘢痕形成的规律 ....................................................................................................................293
一、参与伤口修复的主要细胞成分 ..........................................................................................................293
二、细胞外基质成分 .................................................................................................................................294
三、肉芽组织 .............................................................................................................................................295
四、参与伤口愈合的细胞因子 ..................................................................................................................296
第二节 病理性瘢痕的特征 ............................................................................................................................297
一、病理性瘢痕的特征 ..............................................................................................................................297
二、病理性瘢痕发生的相关因素 ..............................................................................................................297
第三节 病理性瘢痕注射治疗的方案 ...........................................................................................................301
一、适合注射治疗的病理性瘢痕种类 ......................................................................................................301
二、病理性瘢痕常用注射药物 ..................................................................................................................302
第十一章 美塑疗法
第一节 美塑疗法的材料与方法 ....................................................................................................................313
一、美塑疗法的材料 .................................................................................................................................313
二、常用方法 .............................................................................................................................................313
第二节 美塑疗法的适应证与禁忌证 ...........................................................................................................315
一、适应证 .................................................................................................................................................315
二、禁忌证 .................................................................................................................................................316
第三节 美塑疗法的术后处理 ........................................................................................................................317
第十二章 注射美容并发症的诊断与治疗
第一节 面部透明质酸注射相关血管源性并发症 ......................................................................................321
一、病因 .....................................................................................................................................................321
二、危险因素 .............................................................................................................................................321
三、解剖基础 .............................................................................................................................................322
四、临床表现及发病机制 ..........................................................................................................................323
五、体格检查及辅助检查 ..........................................................................................................................325
六、诊断 .....................................................................................................................................................326
七、预防 .....................................................................................................................................................326
八、治疗 .....................................................................................................................................................326
第二节 注射美容术后感染并发症................................................................................................................329
一、病因与诱因 .........................................................................................................................................329
二、临床表现 .............................................................................................................................................330
三、诊断和鉴别诊断 .................................................................................................................................331
四、治疗 .....................................................................................................................................................332
五、预后 .....................................................................................................................................................333
第三节 肉毒毒素相关并发症 ........................................................................................................................334
