Pharmacology is one of indispensable basic courses in medical colleges, and also is one of
professional basic courses for students in various majors of clinical medicine, pharmaceutics
and nursing. Pharmacological science provides an important theoretical basis and experimental
methods for revealing the therapeutic principle to diseases, expounding the innate character
of life activity, promoting the development of biological science. Pharmacology is the study
of interaction between drugs and the body, the bridge between basic medicine and clinical
medicine, the sharing resource between medicine and pharmacy. In recent decades, it appears
new advances in change of disease spectrum, in requirement of public health, in research and
development of new drug. With these advances, pharmacology shows the more and more
importance and applicability.
The goal of this textbook is to provide a succinct, accurate, up-to-date, clinically relevant
introduction to drug action, mechanism of action, clinical uses, adverse drug reaction, drug
interaction, et al., on which rational therapeutics is based. The authors have aimed to make the
textbook readable and useful in learning Pharmacology for the foreign medical student studying
in China, and also suitable for five-year program medical students.
In our long-term teaching for international medical students and on the basis of the
first four editions textbook of pharmacology, this textbook not only affords students basic
knowledge and theories, but also lays a foundation for clinical courses. According to the
development of pharmacology and drug research, many chapters have been updated. At the
same time, it introduces some new drugs and new mechanisms of actions, especially the trends
of pharmacology. The content of this textbook includes six sections, i.e., general introduction,
autonomic nervous system drugs, central nervous system drugs, cardiovascular system drugs,
internal organ and endocrine system drugs, and chemotherapeutic drugs.
The reference books used are as follows: Brunton L L, et al. 2011. Goodman and Gilman¡¯s
The Pharmacological Basis of Therapeutics, 12th Edi; Katzung B G, et al. 2012. Basic and Clinical
Pharmacology 12th Edi; Rang H P, et al. 2011. Rang and Dale¡¯s Pharmacology 7th Edi; Yang B F.
2009. Pharmacology 7th Edi; Lin Z B, et al. 2008. Basis of Medical Pharmacology. 6th Edi; Finkel R,
et al. 2009. Lippincott¡¯s Illustrated Reviews: Pharmacology, 4th Edi.
This textbook is written by faculty members of the Department of Pharmacology, Tianjin
Medical University. Since our ability and level are limited, there maybe some mistakes and
shortcomings in this textbook. I hope the readers give valuable opinions and comments. Any
suggestion and comment are always welcome at anytime to send to author¡¯s E-mail. We have
the capacity and ingenuity to correct these mistakes and shortcomings in next edition.
LOU Jianshi
Department of Pharmacology
School of Basic Medicine
Tianjin Medical University
Tianjin 300070, P.R.China
jianshilou@tijmu.edu.cn
November 2014