This book takes the economic changes and enterprise development in the society in the 40 years of China’s reform and opening up as the main background. It is based on the content and main findings of the Chinese Entrepreneur Survey System from 1993 to 2017, and it also refers to the China Statistical Yearbook, China Statistical Yearbook on Science and Technology, World Intellectual Property Statistics, and 2016 Global Manufacturing Competitiveness Index of Deloitte’s. From the three perspectives of the development history of entrepreneurs, the change of environment in the new age, and new historical mission of entrepreneurs, this book summarizes the development track of China’s entrepreneurial team and the evolution of entrepreneurial spirit, analyzes the change factors and the existing problems, and in the meantime proposes corresponding policy recommendations.